Potential role of transforming growth factor beta1 in drug resistance of tumor cells.
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چکیده
منابع مشابه
Potential role of transforming growth factor beta1 in drug resistance of tumor cells.
Acquired drug resistance of tumor cells is frequently observed in cancer patients undergoing chemotherapy. We studied murine leukemia L1210 cells sensitive and resistant to the cytotoxic action of cisplatin and showed that cisplatin-resistant leukemia cells were also refractory to TGF beta1-dependent growth inhibition and apoptosis. Addressing the question about the mechanisms responsible for t...
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Acquired drug resistance of tumor cells is frequently observed in cancer patients undergoing chemotherapy. We studied murine leukemia L1210 cells sensitive and resistant to the cytotoxic action of cisplatin and showed that cisplatin-resistant leukemia cells were also refractory to TGF 1-dependent growth inhibition and apoptosis. Addressing the question about the mechanisms responsible for the c...
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 2003
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.2003_3702